News & Events


Unsuitability of HhaI from Thermo Fisher Scientific, and possibly other suppliers, for MS-MLPA
17 November 2016

We have established that HhaI restriction enzymes manufactured by Thermo Fisher Scientific are incompatible with the MS-MLPA technique and can cause aberrant results as they are not inactivated by heat. The same may be true for certain HhaI (isoschizomers) from other suppliers. At this moment, the only restriction enzyme with proven suitability for MS- MLPA is the Promega (R6441) enzyme. Please find more information here.

Come and meet us

If you are attending one of the following meetings, please stop by our booth to learn more about how MLPA can be used to benefit your DNA, RNA or methylation analysis.

MRC-Holland booth at a congress
May 27-30 - ESHG. Copenhagen, Denmark


The upcoming MLPA workshops organised by MRC-Holland are listed here.

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MRC-Holland newsletter 2017 May snapshot

new products
P472-SUFU
Familial Medulloblastoma and Meningioma
improved products
P101-STK11
Peutz-Jeghers syndrome (PJS)
P113-FANCB
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P029-WBS
Williams-Beuren syndrome
P437-Familial MDS-AML
Familial MDS-AML
P210-BTK
Agammaglobulinemia
P373-Microdeletion-7
Microdeletion follow-up
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