Solid Tumours
You may also be interested in our brochure MLPA for Tumour Profiling (link opens in a new window).

Product NameApplicationRegion
ME001-Tumour suppressor mix 1basic research Tumour suppressor genes Various
ME002-Tumour suppressor mix 2basic research Tumour suppressor genes Various
ME011-MMR Mismatch repair genes (MMR) MLH1 3p22.2; MSH2 2p21; MSH6 2p16.3; PMS2 7p22.1; EPCAM 2p21; BRAF V600E
ME024-9p21 Tumours, Cutaneous melanoma 9p21: CDKN2A, CDKN2B, and flanking genes
ME042-CIMPbasic research CpG Island methylator phenotype (CIMP) Various
P014-Chromosome 8 Tumour research Chr. 8
P027-Uveal melanoma Uveal melanoma (UM) Chr. 1p, 3, 6, 8
P047-RB1 Retinoblastoma (RB) RB1 13q14.2
P056-TP53CE Li-Fraumeni syndrome (LFS); (Tumour analysis for research use only) TP53 17p13.1
P063-FHIT-WWOX Diverse tumour types, epileptic encephalopathy FHIT (3p14.2) and WWOX (16q23.1)
P078-Breast tumour Breast tumour various
P088-Oligodendroglioma 1p-19q Oligodendroglioma 1p; 19q; IDH1 2q33.3; IDH2 15q26.1; CDKN2A 09p21.3; CDKN2B 09p21.3; CDKN2C 1p33
P105-Glioma-2 Glioma, malignant EGFR, TP53, PTEN + various other
P175-Tumour Gain Tumour Gain various
P181-Centromere mix 1 Centromeric testing Centromeres
P182-Centromere mix 2 Centromeric testing Centromeres
P215-EXT Multiple osteochondromas, hereditary EXT1 8q24.11; EXT2 11p11.2
P225-PTENCE PTEN hamartoma tumor syndrome, Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome, PTEN-related proteus syndrome, Proteus-like syndrome; (Tumour analysis for research use only) PTEN 10q23.31
P251-NB mix 1 Neuroblastoma Chr. 1; 3; 11
P252-NB mix 2 Neuroblastoma Chr. 2 (MYCN); 17
P253-NB mix 3 Neuroblastoma Chr. 4; 7; 9; 12; 14
P258-SMARCB1 Rhabdoid tumors predisposition syndrome SMARCB1 22q11.23
P294-Tumour Loss Tumour loss various
P298-BRAF-HRAS-KRAS-NRASbasic research Various tumour types BRAF 7q34; HRAS 11p15.5; KRAS 12p12.1; NRAS 1p13.2
P301-Medulloblastoma mix 1basic research Medulloblastoma Chr. 6; 14q; 16; 17
P302-Medulloblastoma mix 2basic research Medulloblastoma Chr. 2; 3; 7; 9
P303-Medulloblastoma mix 3basic research Medulloblastoma Chr. 1; 4q; 5q; 8; 10; 20
P308-MET Papillary renal carcinoma; Other cancer types MET 7q31.2; PTEN 10q23.31; LRRK2 12q12
P315-EGFRimproved Tumours, solid EGFR 7p11.2
P323-CDK4-HMGA2-MDM2 Sarcoma; Other tumour types Chr. 12; MDM2 12q15; CDK4 12q14.1; HMGA2 12q14.3
P376-BRCA1ness BRCA1-like breast cancer profile various
P378-MUTYHCE;MA MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1) MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
P380-Wilms' tumour Wilms tumour various
P417-BAP1 Melanocytic tumours, mesothelioma BAP1, 3p21.1
P419-CDKN2A/2B-CDK4 Familial melanoma CDKN2A, CDKN2B, CDK4, MITF E318K
P429-SDHA-MAX Paraganglioma and pheochromocytoma 5p15.3 and 14q23.3
P433-ARID1A-ARID1B Neuroblastoma, ovarian cancer + various other tumour types + mental retardation ARID1A, ARID1B
P451-Chromosome 16 Breast cancer + various tumour types Chromosome 16
P455-LZTR1 Schwannomatosis LZTR1 22q11.21
P458-Gastric cancer Gastric cancer various
P466-CDC73 HPT jaw tumour syndrome, familial hyperparathyroidism, parathyroid carcinoma CDC73
P472-SUFU Familial Medulloblastoma and Meningioma 10q24.32
P474-CD274-PDCD1LG2-JAK2 Various cancer types CD274 (PDL1), PDCD1LG2 (PDL2), JAK2 at 9p24.1
P476-ZNRF3 Adrenocortical tumours and other solid tumours ZNRF3, 22q12.1
P478-SMARCE1 Meningioma, Coffin-Siris syndrome SMARCE1, 17q21.2
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